{"id":18376,"date":"2017-03-08T12:00:00","date_gmt":"2017-03-08T12:00:00","guid":{"rendered":"https:\/\/dev.inrs.ca\/antioxidants-and-lung-cancer-risk\/"},"modified":"2020-11-13T15:19:40","modified_gmt":"2020-11-13T20:19:40","slug":"antioxidants-and-lung-cancer-risk","status":"publish","type":"post","link":"https:\/\/dev.inrs.ca\/en\/news\/antioxidants-and-lung-cancer-risk\/","title":{"rendered":"Antioxidants and lung cancer risk"},"content":{"rendered":"\n<p><strong>An\u00a0<a href=\"http:\/\/journal.frontiersin.org\/article\/10.3389\/fonc.2017.00023\/full\" target=\"_blank\" rel=\"noreferrer noopener\">epidemiological study<\/a>\u00a0published in\u00a0<em>Frontiers in Oncology<\/em>\u00a0suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. The study authors found that vitamin C appears to reduce the risk of lung cancer in female heavy smokers while beta-carotene, alpha-carotene, beta-cryptoxanthin, and lycopene play the same role in male heavy smokers.\u00a0<\/strong><\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/11\/NEWS_Antioxidants-and-lung-cancer-risk_01.png\" alt=\"\"\/><\/figure><\/div>\n\n\n\n<p>Some of these antioxidants were also associated with a lower lung cancer risk in female moderate smokers and nonsmokers. \u201cOur results suggest that vitamin C protects against lung cancer in women who have never smoked, something that to our knowledge has not been reported previously,\u201d stated postgraduate fellow\u00a0<a href=\"http:\/\/www.lshtm.ac.uk\/aboutus\/people\/shareck.martine\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"broken_link\">Martine Shareck<\/a>, lead author of the study.\u00a0<\/p>\n\n\n\n<p>Data from a case-control study of lung cancer was used in the investigation, one of the few to examine the role of antioxidants like carotenoids and vitamin C by smoking intensity. It is the first study to consider both smoking duration and time since quitting, two key smoking history factors for lung cancer.\u00a0<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>\u201cFor the three most common tumour subtypes, we observed that high intakes of beta-carotene, alpha-carotene, beta-cryptoxanthin, lycopene, and vitamin C were associated with a reduced risk of squamous cell carcinoma, while high intakes of beta-carotene and alpha-carotene lowered the risk of adenocarcinoma. Both medium and high intakes of beta-cryptoxanthin and lycopene reduced the risk of small cell carcinoma.\u201d\u00a0<\/p><cite>Marie-\u00c9lise Parent, professor<\/cite><\/blockquote>\n\n\n\n<p>Cigarette smoking is the foremost risk factor for lung cancer, the leading cause of cancer mortality worldwide. Yet diet can influence the occurrence of this cancer. In light of the study results, the authors conclude it is desirable to promote consumption of fruits and vegetables rich in carotenoids and vitamin C to reduce lung cancer risk in nonsmokers and smokers, including heavy smokers.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>About this publication<\/strong><\/h2>\n\n\n\n<p>Study results are presented in the article \u201cInverse Association between Dietary Intake of Selected Carotenoids and Vitamin C and Risk of Lung Cancer\u201d published in\u00a0<a href=\"http:\/\/journal.frontiersin.org\/journal\/oncology\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Frontiers in Oncology<\/em><\/a>\u00a0by authors Martine Shareck,\u00a0<a href=\"https:\/\/dev.inrs.ca\/en\/research\/professors\/alain-n-rousseau\/\">Marie-Claude Rousseau<\/a>, Anita Koushik, Jack Siemiatycki, and <a href=\"https:\/\/dev.inrs.ca\/en\/research\/professors\/marie-elise-parent\/\">Marie-Elise Parent<\/a>. The research received funding from the National Cancer Institute of Canada, the National Health Research and Development Program, the Medical Research Council of Canada, the Canadian Institutes of Health Research, and Fonds de recherche du Qu\u00e9bec \u2013 Sant\u00e9.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. The study authors found that vitamin C appears to reduce the risk of lung cancer in female heavy smokers while beta-carotene, alpha-carotene, beta-cryptoxanthin, and lycopene play the same role in male heavy smokers.\u00a0<\/p>\n","protected":false},"author":1,"featured_media":18377,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[688],"tags":[],"sectors":[679],"class_list":["post-18376","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innover-a-linrs-en","sectors-sante-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.6 (Yoast SEO v24.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Antioxidants and lung cancer risk | INRS<\/title>\n<meta name=\"description\" content=\"An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. 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