{"id":18069,"date":"2020-05-05T19:48:00","date_gmt":"2020-05-05T19:48:00","guid":{"rendered":"https:\/\/dev.inrs.ca\/detecting-the-covid-19-virus-in-the-field\/"},"modified":"2020-09-15T11:13:10","modified_gmt":"2020-09-15T15:13:10","slug":"detecter-le-virus-de-la-covid-19-sur-le-terrain","status":"publish","type":"post","link":"https:\/\/dev.inrs.ca\/en\/news\/detecting-the-covid-19-virus-in-the-field\/","title":{"rendered":"Detecting the COVID-19 virus in the field"},"content":{"rendered":"\n<p style=\"font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.723), 20px);px\"><strong><strong>Professor <a href=\"https:\/\/dev.inrs.ca\/en\/research\/professors\/jonathan-perreault\/\">Jonathan Perreault<\/a>\u2019s lab at Institut National de la Recherche Scientifique (INRS) is working on a new way to detect the virus behind COVID-19 directly in the field. This innovative method would require no fancy equipment or laboratory, in contrast to current tests.<\/strong><\/strong><\/p>\n\n\n\n<p>\u201cOur detection device could be used in schools and businesses, enabling immediate follow-up on site,\u201d says Jonathan Perreault, a microbiology researcher at INRS. A simple change of colour would show whether the virus were present.<\/p>\n\n\n\n<p>\u201cWe\u2019ve already completed a&nbsp;<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0039914019303923\" target=\"_blank\" rel=\"noreferrer noopener\" class=\"broken_link\">proof of concept<\/a>&nbsp;with DNA sequences equivalent to the flu virus. Now we\u2019re adapting the procedure for COVID-19,\u201d explains Dr. Perreault. \u201cWe\u2019ve already identified genetic sequences for targeting the different strains of this coronavirus.\u201d The research project received a two-year, \u20ac98,000 grant from the&nbsp;<a href=\"https:\/\/www.pasteur.fr\/en\" target=\"_blank\" rel=\"noreferrer noopener\">Institut Pasteur International Network<\/a>&nbsp;Coronavirus Task Force.<\/p>\n\n\n\n<figure class=\"wp-block-gallery columns-2 is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><ul class=\"blocks-gallery-grid\"><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"630\" src=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs.jpg\" alt=\"D\u00e9tecter le virus de la COVID-19 sur le terrain\" data-id=\"12208\" data-full-url=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs.jpg\" data-link=\"https:\/\/dev.inrs.ca\/?attachment_id=12208\" class=\"wp-image-12208\" srcset=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs.jpg 1000w, https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs-300x189.jpg 300w, https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs-768x484.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"786\" src=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/perreault_jonathan_grande.jpg\" alt=\"Jonathan Perreault professeur en microbiologie, biochimie et ARN \u00e0 l\u2019Institut national de la recherche scientifique\" data-id=\"12210\" data-full-url=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/perreault_jonathan_grande.jpg\" data-link=\"https:\/\/dev.inrs.ca\/?attachment_id=12210\" class=\"wp-image-12210\" srcset=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/perreault_jonathan_grande.jpg 1000w, https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/perreault_jonathan_grande-300x236.jpg 300w, https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/perreault_jonathan_grande-768x604.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption class=\"blocks-gallery-item__caption\">Professor Jonathan Perreault<\/figcaption><\/figure><\/li><\/ul><\/figure>\n\n\n\n<p>Before rolling out their new instrument, the research team needs to fine-tune detection. \u201cIs the colour change clear? What viral load can the device detect? Ideally we would like to be able to detect people who are still asymptomatic. We\u2019re also trying to reduce the sample processing steps, such as RNA extraction,\u201d says Dr. Perreault.<\/p>\n\n\n\n<p>The test will be fine tuned with human coronaviruses similar to SARS-CoV-2 in structure but not in infectiousness. For this part of the project, Dr. Perreault is collaborating with Professor&nbsp;<a href=\"https:\/\/dev.inrs.ca\/en\/professors\/pierre-talbot\/\">Pierre Talbot<\/a>&nbsp;from INRS and with Marc Desforges, his former research associate, now a medical biology specialist in the virology lab at CHU-Sainte-Justine in Montr\u00e9al. Next, Dr. Perreault\u2019s lab will test the detection method on cultured SARS-CoV-2 virus from the lab of&nbsp;<a href=\"https:\/\/dev.inrs.ca\/en\/research\/professors\/laurent-chatel-chaix\/\">Laurent Chatel-Chaix<\/a>, and on samples from patients with COVID-19. The goal is to have an initial version of the test to detect 100,000 virus particles or less. Dr. Perreault expects to achieve that goal within six months.<\/p>\n\n\n\n<p>To make the detection process even faster and more sensitive, Dr. Perreault is collaborating with Professor&nbsp;<a href=\"https:\/\/dev.inrs.ca\/en\/professors\/ana-tavares\/\">Ana Tavares<\/a>, an electrochemistry specialist. Together they are developing electrodes that will capture the virus\u2019 DNA sequence. \u201cThe idea is to put a drop on the electrode and see if there\u2019s an electrical signal indicating that the sample is positive,\u201d explains Dr. Perreault. \u201cWe already have a proof of concept with optical fibres. We want to achieve the same results with electrodes, which are easier to manufacture.\u201d He hopes to have a detection prototype within a year.<\/p>\n\n\n\n<div class=\"wp-block-buttons aligncenter is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-darker-background-color has-background\" href=\"https:\/\/dev.inrs.ca\/en\/inrs\/newsroom\/topics\/covid-19-the-unpredictable-enemy\/\">Back to topic<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Professor Jonathan Perreault\u2019s lab at Institut National de la Recherche Scientifique (INRS) is working on a new way to detect the virus behind COVID-19 directly in the field. This innovative method would require no fancy equipment or laboratory, in contrast to current tests.<\/p>\n","protected":false},"author":297,"featured_media":12209,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[688],"tags":[],"sectors":[679],"class_list":["post-18069","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innover-a-linrs-en","sectors-sante-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.6 (Yoast SEO v24.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Detecting the COVID-19 virus in the field | INRS<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Detecting the COVID-19 virus in the field | INRS\" \/>\n<meta property=\"og:description\" content=\"Professor Jonathan Perreault\u2019s lab at Institut National de la Recherche Scientifique (INRS) is working on a new way to detect the virus behind COVID-19 directly in the field. This innovative method would require no fancy equipment or laboratory, in contrast to current tests.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dev.inrs.ca\/en\/news\/detecting-the-covid-19-virus-in-the-field\/\" \/>\n<meta property=\"og:site_name\" content=\"INRS\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/inrsciences\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-05-05T19:48:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-09-15T15:13:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/dev.inrs.ca\/wp-content\/uploads\/2020\/07\/Actualite-detecter-le-virus-de-la-COVID-19-sur-le-terrain-inrs.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Simon Desbiens\" \/>\n<meta name=\"twitter:card\" 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